The Cottrell Lab

The Cottrell Lab is hiring a Research Assistant! For more information and to apply, please visit the Queen's University Careers job posting.

The Cottrell Lab is looking for post-doctoral fellows! Expertise in one or more of the following is required: tumour microenvironment, bioinformatics, anatomic pathology, and/or immunology. Interested? Email your cover letter and CV to cottrell.laboratory@gmail.com.

Photograph of Dr. Tricia Cottrell

Dr. Tricia Cottrell is a clinician scientist whose research focuses on tumour-immune interactions in solid tumours, and the identification of predictive and prognostic biomarkers in pre-treatment and post-treatment tumour tissues. Cottrell completed her MD, PhD, Anatomic Pathology Residency, and post-doctoral training at the Johns Hopkins University School of Medicine and is now an Assistant Professor in the Department of Pathology and Molecular Medicine at Queen’s University in Kingston, ON.

One of Dr. Cottrell’s key research contributions was the first characterization of the features of immune-mediated tumour regression following neoadjuvant anti-PD-1 therapy in non-small cell lung carcinoma (NSCLC). This published clinical trial was used to develop a set of proposed immune-related pathologic response criteria for the standardized and reproducible assessment of pathologic response following neoadjuvant immunotherapy. These criteria are now being evaluated in a large clinical trial of neoadjuvant anti-PD-1 therapy in NSCLC. These findings have also been extended to other tumor types and efforts to develop a pan-cancer method for quantifying pathologic response are underway.

Current affiliations

Research interests

  • Tumour-immune microenvironment

  • Immuno-oncology

  • Pathology

  • Immunology

  • Lung cancer

  • Multiplex immunofluorescence



Contact

Dr. Tricia Cottrell: trc3@queensu.ca

Select publications

See Dr. Cottrell’s publications on PubMed or on Google Scholar.